This a model from the article:
A role for calcium release-activated current (CRAC) in cholinergic modulation ofelectrical activity in pancreatic beta-cells.
Bertram R, Smolen P, Sherman A, Mears D, Atwater I, Martin F, Soria B. Biophys J1995 Jun;68(6):2323-32 7647236,
Abstract:
S. Bordin and colleagues have proposed that the depolarizing effects ofacetylcholine and other muscarinic agonists on pancreatic beta-cells aremediated by a calcium release-activated current (CRAC). We support thishypothesis with additional data, and present a theoretical model which accountsfor most known data on muscarinic effects. Additional phenomena, such as thebiphasic responses of beta-cells to changes in glucose concentration and thedepolarizing effects of the sarco-endoplasmic reticulum calcium ATPase pumppoison thapsigargin, are also accounted for by our model. The ability of thissingle hypothesis, that CRAC is present in beta-cells, to explain so manyphenomena motivates a more complete characterization of this current.
This model was taken from the CellML repository and automatically converted to SBML.
The original model was: Bertram R, Smolen P, Sherman A, Mears D, Atwater I, Martin F, Soria B. (1995) - version=1.0
The original CellML model was created by:
Catherine Lloyd
c.lloyd@auckland.ac.nz
The University of Auckland
This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team.
For more information see the terms of use.
To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.
And translate the model using SBMLtoOdin::importSBMLfromBioModels(BioModel_ID, file_name)
Project idea and SBMLtoOdin: Leonie Lorenz and John Lees,
Development of Menelmacar website: Antoine Andréoletti,
Web design: Andrea Epifani, Zeqing Lu (Gomoku Studio)
Models are sourced from EMBL-EBI's